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Deep cervical lymph nodes
Deep Lymph Nodes
  1. Submental
  2. Submandibular (Submaxillary)
Anterior Cervical Lymph Nodes (Deep)
  1. Prelaryngeal
  2. Thyroid
  3. Pretracheal
  4. Paratracheal
Deep Cervical Lymph Nodes
  1. Lateral jugular
  2. Anterior jugular
  3. Jugulodigastric
Inferior Deep Cervical Lymph Nodes
  1. Juguloomohyoid
  2. Supraclavicular (scalene)
Details
SystemLymphatic system
Drains toJugular trunk
Identifiers
Latinnodi lymphoidei cervicales profundi
Anatomical terminology

The deep cervical lymph nodes are a group of cervical lymph nodes in the neck[1] that form a chain along the internal jugular vein within the carotid sheath.[2]

Structure

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Classification

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The deep cervical lymph nodes are subdivided into a superior group and an inferior group.[3][4]

Alternatively, they can be divided into deep anterior cervical lymph nodes and deep lateral cervical lymph nodes.[citation needed]

They can also be divided into three groups: "superior deep jugular", "middle deep jugular", and "inferior deep jugular".[5][6]

Relations

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The deep cervical lymph nodes are contained in the carotid sheath in the neck, close to the internal jugular vein.[7] They connect to the meningeal lymphatic vessels superiorly.[8][9]

Afferents

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All lymphatic vessels of the head and neck ultimately drain to the deep cervical lymph nodes - either by way of other lymph nodes or directly from tissues.[4]

The deep cervical lymph nodes serve as the principal drainage site for both lymphatic fluid and cerebrospinal fluid carried by the meningeal lymphatic vessels of the central nervous system, making them the primary site of immune surveillance for CNS-derived antigens.[10]

Efferents

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Efferents of the deep cervical lymph nodes form the ipsilateral jugular trunk.[4]

References

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  1. ^ Ellis H, Standring S, Gray HD (2005). Gray's anatomy: the anatomical basis of clinical practice. St. Louis, Mo: Elsevier Churchill Livingstone. p. 936. ISBN 0-443-07168-3.
  2. ^ Fehrenbach, Margaret J.; Herring, Susan W. (2017). Illustrated Anatomy of the Head and Neck (5th ed.). St. Louis: Elsevier. p. 148. ISBN 978-0-323-39634-9.
  3. ^ Dalley AF, Moore KL (2006). Clinically oriented anatomy. Hagerstown, MD: Lippincott Williams & Wilkins. p. 356. ISBN 0-7817-3639-0.
  4. ^ a b c Standring, Susan (2020). Gray's Anatomy: The Anatomical Basis of Clinical Practice (42th ed.). New York. p. 593. ISBN 978-0-7020-7707-4. OCLC 1201341621.{{cite book}}: CS1 maint: location missing publisher (link)
  5. ^ "Lymphatic drainage and fascial planes in the neck". Archived from the original on 2008-02-16.
  6. ^ Core Curriculum: Review of Neck Anatomy Archived 2008-05-17 at the Wayback Machine
  7. ^ Woodward PJ, Griffith JF, Antonio GE, Ahuja AT, eds. (2018-01-01). "Midcervical Level". Imaging Anatomy: Ultrasound (Second ed.). Elsevier. pp. 118–123. ISBN 978-0-323-54800-7.
  8. ^ Anrather J (2017-01-01). "Chapter 28 - Pathophysiology of the Peripheral Immune Response in Acute Ischemic Stroke". In Caplan LR, Biller J, Leary MC, Lo EH (eds.). Primer on Cerebrovascular Diseases (Second ed.). San Diego: Academic Press. pp. 139–145. ISBN 978-0-12-803058-5.
  9. ^ Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, et al. (July 2015). "Structural and functional features of central nervous system lymphatic vessels". Nature. 523 (7560): 337–41. Bibcode:2015Natur.523..337L. doi:10.1038/nature14432. PMC 4506234. PMID 26030524.
  10. ^ Zhang, Q., Niu, Y., Li, Y. et al. Meningeal lymphatic drainage: novel insights into central nervous system disease. Sig Transduct Target Ther 10, 142 (2025). https://doi.org/10.1038/s41392-025-02177-z


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