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Not to be confused with Janeway lesion.
For other Osler's signs, see Osler's sign (disambiguation).
Osler's node
Osler's lesions found on the hand and fingers of a 43-year-old male with subacute bacterial endocarditis
Differential diagnosisinfective endocarditis

Osler's nodes are painful, red, raised lesions found typically on the hands and feet.[1] They are associated with a number of conditions, including infective endocarditis, and are caused by immune complex deposition. Their presence is one definition of Osler's sign.[2]

Causes

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Osler's nodes result from the deposition of immune complexes.[3] The resulting inflammatory response leads to swelling, redness, and pain that characterize these lesions.

The nodes are commonly indicative of subacute bacterial endocarditis.[4] 10–25% of endocarditis patients will have Osler's nodes.[5] Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender.[3]

Osler's nodes can also be seen in

Etymology

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Osler's nodes are named after Sir William Osler who described them in the early twentieth century.[6][7] He described them as "ephemeral spots of a painful nodular erythema, chiefly in the skin of the hands and feet."[1]

References

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  1. ^ a b Parashar, Krishan; Daveluy, Steven (2022). "Osler Node and Janeway Lesions". StatPearls. StatPearls Publishing. PMID 32491553.
  2. ^ "Osler sign" at Dorland's Medical Dictionary
  3. ^ a b Farrior, JB; Silverman, ME (August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis" (PDF). Chest. 70 (2): 239–43. doi:10.1378/chest.70.2.239. PMID 947688. Archived from the original (PDF) on 2014-05-14. Retrieved 2013-08-10.
  4. ^ "Osler nodes" at Dorland's Medical Dictionary
  5. ^ "Endocarditis". The Lecturio Medical Concept Library. Retrieved 19 July 2021.
  6. ^ synd/1702 at Whonamedit?
  7. ^ Osler, W (1908–1909). "Chronic infectious endocarditis". Quarterly Journal of Medicine. 2. Oxford: 219–230.

📚 Artikel Terkait di Wikipedia

Janeway lesion

associated with infective endocarditis and often indistinguishable from Osler's nodes. Janeway lesions are painless, frequently haemorrhagic lesions seen

Endocarditis

feeling, cardiac murmur, heart failure, petechia (red spots on the skin), Osler's nodes (subcutaneous nodules found on hands and feet), Janeway lesions (nodular

William Osler

endocarditis. Osler described them as "ephemeral spots of a painful nodular erythema, chiefly in the skin of the hands and feet." Osler nodes are usually

Osler

named after Edmund Boyd Osler Hereditary hemorrhagic telangiectasia, or Osler's disease, named for Sir William Osler Osler's nodes, painful, red, raised

Lesion

Brain lesions Olney's lesions Skin lesions Melanocytic nevus Skip lesion Osler's node Keratoderma blennorrhagicum Dermatosis papulosa nigra Leukemid Janeway

List of medical symptoms

through 9)) blister (T14.0) edema (R60) itching (L29) Janeway lesions and Osler's node laceration rash (R21) urticaria (L50) Neurological abnormal posturing

Granulicatella adiacens

produces detectable vegetations, although other classic IE signs (e.g., Osler nodes) are usually not present. Treatment failure is frequently observed, and

Osler's sign

Osler's sign may refer to: Osler's sign, pseudohypertension Osler's sign, pretibial myxedema Osler's sign, Osler's node, which are nodes associated with