Depiction of a cell passing through a microchannel

Microchannel in microtechnology is a channel with a hydraulic diameter below 1 mm, usually 1–99 μm.[1] Microchannels are used in fluid control (see Microfluidics), heat transfer (see Micro heat exchanger) and cell migration observation.[2] They are more efficient than their 'macro' counterparts, because of a high surface-area to volume ratio yet pose a multitude of challenges due to their small size.[3]

Materials

edit

Different types of materials are required for the different uses of microchannels. These are the three main categories.[4]

Polymeric and glass substrates

edit

Polymethyl methacrylate (PMMA) is used as a solution to a wide range of microfluidic devices due to its low cost and easier fabricating methods.[4] Silicon elastomers can be used for situations in which elasticity and deformation is necessary.[5]

Metallic substrates

edit

Metallic substrates are often chosen for their advantageous metallic properties, such as withstanding high temperatures and transferring heat faster. They can be subject to corrosion.[4][6]

Semiconductors, ceramics and composites

edit

Ceramic materials allow for high-temperature operation in comparison to metallic substrates and enable operation in harsh chemical environments in which metals cannot be used.[7]

History

edit

The concept of the microchannel was proposed for the first time by researchers Tuckerman and Pease of Stanford Electronics Laboratories in 1981.[8] They suggested an effective method for designing microchannels in the laminar and fully developed flow.[9]

Common uses

edit

Microchannels are extensively used in the pharmaceuticals, and biochemical industries due to short diffusion distances, higher interfacial area, and higher heat/mass transfer rates.[10]

See also

edit

Sources

edit
  1. ^ Kandlikar, Satish G. (2006). Heat transfer and fluid flow in minichannels and microchannels. Amsterdam, the Netherlands: Elsevier B.V. pp. 450. ISBN 978-0-08-044527-4.
  2. ^ "Microchannels". 4Dcell. Retrieved 2022-07-15.
  3. ^ Puccio, Kris (2020-02-10). "Understanding Microchannel Heat Exchangers & Their Use Cases". Therma. Retrieved 2022-07-15.
  4. ^ a b c Prakash, Shashi; Kumar, Subrata. "Fabrication of microchannels: A review". Journal of Engineering Manufacture. 229 (8).
  5. ^ Yuen, Michelle; Kramer, Rebecca. "Fabricating microchannels in elastomer substrates for stretchable electronics" (PDF). MSEC Science.
  6. ^ Andou, F.; Yamamoto, A.; Kawai, T.; Ohmori, H.; Ishida, T.; Takeuchi, Y. (2007-01-01), Arai, Eiji; Arai, Tatsuo (eds.), "MICROCHANNEL ARRAY CREATION BY MEANS OF ULTRAPRECISION MACHINING", Mechatronics for Safety, Security and Dependability in a New Era, Oxford: Elsevier, pp. 163–168, ISBN 978-0-08-044963-0, retrieved 2022-07-15{{citation}}: CS1 maint: work parameter with ISBN (link)
  7. ^ Kee, Robert J.; Almand, Berkeley B.; Blasi, Justin M.; Rosen, Benjamin L.; Hartmann, Marco; Sullivan, Neal P.; Zhu, Huayang; Manerbino, Anthony R.; Menzer, Sophie; Coors, W. Grover; Martin, Jerry L. (2011-08-01). "The design, fabrication, and evaluation of a ceramic counter-flow microchannel heat exchanger". Applied Thermal Engineering. 31 (11): 2004–2012. Bibcode:2011AppTE..31.2004K. doi:10.1016/j.applthermaleng.2011.03.009. ISSN 1359-4311.
  8. ^ Tuckerman, D. B., & Pease, R. F. W. (1981). High-performance heat sinking for VLSI. IEEE Electron device letters, 2(5), 126-129. https://dx.doi.org/10.1109/EDL.1981.25367
  9. ^ Salimpour, M. R., Al-Sammarraie, A. T., Forouzandeh, A., & Farzaneh, M. (2019). Constructal design of circular multilayer microchannel heat sinks. Journal of Thermal Science and Engineering Applications, 11(1), 011001. https://dx.doi.org/10.1115/1.4041196
  10. ^ Jaiswal, P., Kumar, U., Biswas, K. G.(2021) Liquid-Liquid Flow through Micro Dimensional Reactors: A Review on Hydrodynamics, Mass Transfer, and Reaction Kinetics. Exp. Comput. Multiph. Flow 2021. https://doi.org/10.1007/s42757-020-0092-0


📚 Artikel Terkait di Wikipedia

Microchannel

Microchannel may refer to: Microchannel (microtechnology), used in fluid control, heat transfer cell migration observation Micro Channel architecture,

Microreactor

A microreactor or microstructured reactor or microchannel reactor is a device in which chemical reactions take place in a confinement with typical lateral

Micro heat exchanger

microchannels, which are channels with a hydraulic diameter below 1 mm. Microchannel heat exchangers can be made from metal or ceramic. Microchannel heat

Micro process engineering

volumina, typically inside channels with diameters of less than 1 mm (microchannels) or other structures with sub-millimeter dimensions. These processes

Bio-MEMS

of heterogeneous laminar flows for selective treatment of cells in microchannels Today, hydrogels such as agarose, biocompatible photoresists, and self-assembly

Amit Agrawal

Converging Microchannels". Journal of Fluids Engineering. 139 (6): 061203–061203–9. doi:10.1115/1.4035945. ISSN 0098-2202. Microchannel (microtechnology) Microtechnology

Ion track

diameter. Etched track cylinders can be used as filters, Coulter counter microchannels, be modified with monolayers, or be filled by electroplating. Ion track

Stéphanie P. Lacour

Technology in Lausanne (EPFL) as a tenure track assistant professor of microtechnology and bioengineering at the School of Engineering. In 2016, Lacour was