GPR123 (nama resmi: ADGRA1) adalah protein pada manusia disandi oleh gen GPR123.[3][4] GPR123 adalah anggota dari keluarga reseptor GPCR adhesi. Anggota keluarga biasanya ditandai dengan daerah ekstraseluler diperpanjang dengan sejumlah variabel domain protein digabungkan ke domain TM7 melalui domain dikenal sebagai domain GAIN (GPCR-Autoproteolysis INducing).[5][6][7]
Referensi
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^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (Feb 2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini". Biochem Biophys Res Commun. 301 (3): 725–34. doi:10.1016/S0006-291X(03)00026-3. PMID12565841.
Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res
system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism". Cellular and Molecular Life Sciences. 73 (17): 3221–3247
Orwick-Rydmark M, Habeck M, Alva V, Arnold T, Linke D (2017). "An evolutionarily conserved glycine-tyrosine motif forms a folding core in outer membrane proteins"
PNPase, exosome and RNA helicases as the building components of evolutionarily-conserved RNA degradation machines". Journal of Biomedical Science. 14 (4):
Padmanabhan A, Vuong SA, Hochstrasser M (March 2016). "Assembly of an Evolutionarily Conserved Alternative Proteasome Isoform in Human Cells". Cell Reports. 14
